July 2021: Congratulations to Yucheng on the paper entitled "Caspases switch off m6A RNA modification pathway to foster the replication of a ubiquitous human tumor virus" accepted for publication on mBio with Dr. Renfeng Li's lab from VCU. Good job!
July 2021: Congratulations to Shuyi, Sheng, and all authors on the paper entitled "Updated SARS-CoV-2 Single Nucleotide Variants and Mortality Association" accepted for publication on Journal of Medical Virology (https://onlinelibrary.wiley.com/share/author/CT9JJHUHGN7AVYZVBFI8?target=10.1002/jmv.27191). Well done!
May 2021: Congratulations to Dr. Wan on his IUSCCC Near-Miss grant with Dr. Chang-Deng Hu!
November 2020: Congratulations to Shuyi for receiving the award of Best Oral Presentation at CCBB 2020 Retreat. Good job!
September 2020: Our paper entitled "GESS: A database of Global Evaluation of SARS-CoV-2/hCoV-19 Sequences" has been accepted for publication on Nucleic Acids Research. Congratulations to Shuyi, Kailing, Sheng, and all authors.
September 2020: Another PRMT5 work, "Protein arginine methyltransferase 5 promotes androgen receptor transcription in a pICln-dependent manner in castration-resistant prostate cancer", in collaboration with Dr. Chang-Deng Hu's lab has been accepted for publication on Cancer Research. Congratulations to Shuyi, Sheng, Dr. Hu's lab, and all authors.
September 2020: Our first COVID-19 paper entitled "Genetic spectrum and distinct evolution patterns of SARS-CoV-2" was accepted for publicatoin on Frontiers in Microbiology. Congratulations to Sheng, Shuyi, Kailing, and all our collaborators!
September 2020: Welcome Dr. Yucheng Zhang to join our lab from University of Florida.
July 2020: The paper in collaboration with Dr. Lei Yang’s lab entitled “Genome-wide studies reveal the essential and opposite roles of ARID1A in controlling human cardiogenesis and neurogenesis from pluripotent stem cells” was published online in Genome Biology. Congratulations to Sheng, Dr. Yang's lab, and all authors.
July 2020: Thanks to the Walther Cancer Foundation, IUSCCC, and IUSM for another five-year financial support on the C3B led by Dr. Jun Wan.
December 2019: Welcome Dr. Jilong Bian to join our lab. Dr. Bian is a visiting scholar from Northeast Forestry University. His research interest is about computer vision, deep learning and bioinformatics.
November 2019: Q&A with Dr. Jun Wan about the C3B was published in IUSCC news.
November 2019: In long-term collaboration with Dr. Chang-Deng Hu's lab at Purdue University, the paper entitled “PRMT5 cooperates with pICln to function as a master epigenetic activator of DNA double-strand break repair genes” was published in iScience. Congratulations to Sheng, Dr. Hu's lab, and all authors.
October 2019: Our teamwork together with Drs. Jingwu Xie and Jiali Han’s labs on “Distinct Transcriptomic Landscapes of Cutaneous Basal Cell Carcinomas and Squamous Cell Carcinomas” was published in Genes & Diseases. Congratulations to all authors!
August 2019: Our article "Follicular regulatory T cells inhibit the development of granzyme B–expressing follicular helper T cells" in collaboration with Dr. Alex Dent was published in JCI Insight. Congratulations to Shuyi and all authors.
September 2019: The featured interview with Dr. Nadia Atallah and Dr. Jun Wan at C3B, "A case for personalized medicine in the search for answers about cancer", was published in Purdue University Research Foundation News .
August 2019: Welcome Mr. Kailing Li to join our lab as a PhD student. Kailing received his master degree in Computer Science from SUNY- University at Albany.
July 2019: Congratulations to our Indiana University Simon Cancer Center (IUSCC) for being promoted to NCI-comprehensive cancer center. The Cancer Bioinformatics Core led by Dr. Jun Wan is also successfully funded through CCGS grant for five more years.
July 2018: Another paper about our most recent study “Analysis of KLF4 regulated genes in cancer cells reveals a role of DNA methylation in promoter-enhancer interactions” has been published in Epigenetics. Congratulations!
August 2017: Welcome Ms. Shuyi Fang to join our lab as a PhD student. Shuyi got her bachelor degree from Tongji University.
July 2017: Welcome Dr. Sheng Liu to join our lab as research associate. Prior to Indiana University, Dr. Liu had the postdoc training in Johns Hopkins University.
May 2017: Our study on KLF4 DNA methylation-dependent binding has been published in eLife. The paper was entitled “Methylated cis-regulatory elements mediate KLF4-dependent gene transactivation and cell migration”. Congratulations!